Aging of the erythrocyte. IX. Fluorescence studies on changes in membrane properties

G. Bartosz, G. Szabo, J. Szöllősi, J. Szöllösi, S. Damjanovich

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Fluorescence studies of membranes prepared from density-separated red blood cells demonstrated an increase in lipid viscosity (judging from fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene and 1-aminonaphthalane-8-sulfonate and changes in the physical state of proteins (judging from tryptophan fluorescence intensity and polarization). These alterations may be partly due to lipid peroxidation. In vivo accumulation of products of this process in the membranes was confirmed. Changes were also found in the distribution pattern of cell populations of different mean age in a cell sorter, probably due to alterations in rheological properties of the erythrocytes.

Original languageEnglish
Pages (from-to)265-274
Number of pages10
JournalMechanisms of Ageing and Development
Volume16
Issue number3
DOIs
Publication statusPublished - 1981

Fingerprint

Erythrocyte Aging
Fluorescence Polarization
Aging of materials
Erythrocytes
Fluorescence
Diphenylhexatriene
Membranes
Cells
Viscosity
Tryptophan
Polarization
Lipid Peroxidation
Lipids
Blood
Population
Proteins

ASJC Scopus subject areas

  • Ageing
  • Biochemistry
  • Developmental Biology
  • Developmental Neuroscience

Cite this

Aging of the erythrocyte. IX. Fluorescence studies on changes in membrane properties. / Bartosz, G.; Szabo, G.; Szöllősi, J.; Szöllösi, J.; Damjanovich, S.

In: Mechanisms of Ageing and Development, Vol. 16, No. 3, 1981, p. 265-274.

Research output: Contribution to journalArticle

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