Aggristin (ristomycin) precipitation test

a new tool for the detection of fibrin monomer and fibrin degradation products.

G. Pfliegler, G. Vogel, Z. Boda, G. Zajka, K. Rak

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The specific detection of fibrin monomer and fibrin degradation products is of high importance in the laboratory diagnosis of intravascular clotting (disseminated intravascular coagulation, deep vein thrombosis). The methods proposed until now are partly time-consuming, needing special laboratories or insensitive and poorly specific. Applying ristomycin instead of ristocetin (another member of the vancomycin antibiotics) a new simple, specific and sensitive method has been elaborated and recommended for the laboratory diagnosis of intravascular coagulation and its differentiation from primary fibrinogenolysis. The results obtained from in vitro and animal experiments and from human studies are presented.

Original languageEnglish
Pages (from-to)629-635
Number of pages7
JournalFolia haematologica : internationales Magazin fur klinische und morphologische Blutforschung
Volume112
Issue number4
Publication statusPublished - 1985

Fingerprint

Ristocetin
Fibrin Fibrinogen Degradation Products
Clinical Laboratory Techniques
Disseminated Intravascular Coagulation
Vancomycin
Venous Thrombosis
Anti-Bacterial Agents
fibrinmonomer
In Vitro Techniques

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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abstract = "The specific detection of fibrin monomer and fibrin degradation products is of high importance in the laboratory diagnosis of intravascular clotting (disseminated intravascular coagulation, deep vein thrombosis). The methods proposed until now are partly time-consuming, needing special laboratories or insensitive and poorly specific. Applying ristomycin instead of ristocetin (another member of the vancomycin antibiotics) a new simple, specific and sensitive method has been elaborated and recommended for the laboratory diagnosis of intravascular coagulation and its differentiation from primary fibrinogenolysis. The results obtained from in vitro and animal experiments and from human studies are presented.",
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T1 - Aggristin (ristomycin) precipitation test

T2 - a new tool for the detection of fibrin monomer and fibrin degradation products.

AU - Pfliegler, G.

AU - Vogel, G.

AU - Boda, Z.

AU - Zajka, G.

AU - Rak, K.

PY - 1985

Y1 - 1985

N2 - The specific detection of fibrin monomer and fibrin degradation products is of high importance in the laboratory diagnosis of intravascular clotting (disseminated intravascular coagulation, deep vein thrombosis). The methods proposed until now are partly time-consuming, needing special laboratories or insensitive and poorly specific. Applying ristomycin instead of ristocetin (another member of the vancomycin antibiotics) a new simple, specific and sensitive method has been elaborated and recommended for the laboratory diagnosis of intravascular coagulation and its differentiation from primary fibrinogenolysis. The results obtained from in vitro and animal experiments and from human studies are presented.

AB - The specific detection of fibrin monomer and fibrin degradation products is of high importance in the laboratory diagnosis of intravascular clotting (disseminated intravascular coagulation, deep vein thrombosis). The methods proposed until now are partly time-consuming, needing special laboratories or insensitive and poorly specific. Applying ristomycin instead of ristocetin (another member of the vancomycin antibiotics) a new simple, specific and sensitive method has been elaborated and recommended for the laboratory diagnosis of intravascular coagulation and its differentiation from primary fibrinogenolysis. The results obtained from in vitro and animal experiments and from human studies are presented.

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