Aetiology and antifungal susceptibility of yeast bloodstream infections in a Hungarian University Hospital between 1996 and 2000

I. Dóczi, Erika Dósa, Edit Hajdú, E. Nagy

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Abstract

The purpose of this study was to evaluate the aetiology and susceptibility of different Candida species originating from blood cultures received from different clinical wards of the University Hospital in Szeged, Hungary, from 1996 to 2000. A total of 145 episodes of fungaemia occurred in 68 patients. In 73.5% of the patients the infections were due to Candida albicans, 7.3% to C. parapsilosis, 5.9% to C. krusei, 4.4% to C. tropicalis and 3% each to C. glabrata, other Candida spp. and Cryptococcus neoformans. There were no appreciable differences in the distribution of yeast species during the 5-year period: C. albicans remained the predominant species causing bloodstream infections in this hospital, similar to the results of other studies (Norway, SENTRY Program in USA, Canada and South America). Most of the Candida isolates (39.3%) were from blood cultures of patients hospitalised in surgical wards, 28.3% were from adult intensive care units (ICUs), 13.8% from paediatric ICUs, 11% from haematology and 7.6% from cardiology departments. MICs for amphotericin B, fluconazole and itraconazole were determined for 83% of the isolates. All isolates were susceptible to amphotericin B. The percentage of yeast isolates with decreased susceptibility or resistance to fluconazole was smaller (15.7%) than that for itraconazole (24%).

Original languageEnglish
Pages (from-to)677-681
Number of pages5
JournalJournal of Medical Microbiology
Volume51
Issue number8
Publication statusPublished - 2002

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Itraconazole
Fluconazole
Yeasts
Amphotericin B
Candida albicans
Candida
Infection
Fungemia
Candida glabrata
Pediatric Intensive Care Units
Cryptococcus neoformans
Hungary
South America
Hematology
Norway
Cross Infection
Cardiology
Canada
Intensive Care Units
Blood Culture

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

Cite this

Aetiology and antifungal susceptibility of yeast bloodstream infections in a Hungarian University Hospital between 1996 and 2000. / Dóczi, I.; Dósa, Erika; Hajdú, Edit; Nagy, E.

In: Journal of Medical Microbiology, Vol. 51, No. 8, 2002, p. 677-681.

Research output: Contribution to journalArticle

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