Adverse effects of dopamine potentiation by long-term treatment with selegiline

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A patient with triosephosphate isomerase (TPI) deficiency exhibited worsening of abnormal involuntary movements of the dystonic type and developed psychiatric symptoms while on selegiline. When selegiline was stopped after 9 years of treatment, abnormal involuntary movements improved to pretreatment level and psychiatric behaviour returned to normal. Monoamine oxidase-B platelet activity was low in this patient.

Original languageEnglish
Pages (from-to)107-109
Number of pages3
JournalMovement Disorders
Volume19
Issue number1
DOIs
Publication statusPublished - Jan 1 2004

Keywords

  • Monoamine oxidase-B
  • Selegiline
  • TPI defect
  • Triosephosphate isomerase

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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