Advancements in brachytherapy

Kari Tanderup, Cynthia Ménard, Csaba Polgar, Jacob Christian Lindegaard, Christian Kirisits, Richard Pötter

Research output: Contribution to journalReview article

20 Citations (Scopus)

Abstract

Brachytherapy is a radiotherapy modality associated with a highly focal dose distribution. Brachytherapy treats the cancer tissue from the inside, and the radiation does not travel through healthy tissue to reach the target as with external beam radiotherapy techniques. The nature of brachytherapy makes it attractive for boosting limited size target volumes to very high doses while sparing normal tissues. Significant developments over the last decades have increased the use of 3D image guided procedures with the utilization of CT, MRI, US and PET. This has taken brachytherapy to a new level in terms of controlling dose and demonstrating excellent clinical outcome. Interests in focal, hypofractionated and adaptive treatments are increasing, and brachytherapy has significant potential to develop further in these directions with current and new treatment indications.

Original languageEnglish
Pages (from-to)15-25
Number of pages11
JournalAdvanced Drug Delivery Reviews
Volume109
DOIs
Publication statusPublished - Jan 15 2017

Keywords

  • Brachytherapy
  • Focal therapy
  • Hypofractionation
  • Image guided therapy
  • Imaging
  • Radiotherapy
  • Technology

ASJC Scopus subject areas

  • Pharmaceutical Science

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    Tanderup, K., Ménard, C., Polgar, C., Lindegaard, J. C., Kirisits, C., & Pötter, R. (2017). Advancements in brachytherapy. Advanced Drug Delivery Reviews, 109, 15-25. https://doi.org/10.1016/j.addr.2016.09.002