Administration of preemptive analgesia by diclofenac to prevent acute postcraniotomy headache

Éva Simon, Judit Bánk, Judit Gál, Péter Siró, Lászĺo Novák, B. Fülesdi, Csilla Molnár

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Purpose - Posteraniotomy headache (PCH) is a frequent perioperative complication in neuroanesthesia. The aim of the present work was to assess the incidence of PCH and to test the efficacy and safety of preoperatively administered diclofenac. Methods - Patients undergoing craniotomies for intracranial tumor resections were enrolled. In the case group 100 mg diclofenac p.o. one hour prior to surgery was used as a preemptive analgesic along with infiltration of the surgical site with a combination of lidocaine and epinephrine. In controls only surgical site infiltration was used. VAS scores were assessed preoperatively, on the day of surgery (DoS), on the 1st and 5th postoperative days. Results - We have found that PCH of any severity is between 50-90% during the first five days after surgery. The number of cases characterized as "no pain" significantly decreased in the early postoperative period, but remained in both groups still higher on the 5th postoperative day than observed preoperatively. In both groups, the number of headaches characterized as mild pain remained relatively stable and substantial increases in case numbers were observed in moderate and severe headaches, showing a declining tendency over time in the postoperative period. A significant effect of diclofenac pretreatment was observed compared to controls on DoS (χ2: 10.429, p2: 8.75, p2: 14.3, p

Original languageEnglish
Pages (from-to)302-306
Number of pages5
JournalIdeggyógyászati szemle
Volume65
Issue number9-10
Publication statusPublished - Sep 30 2012

Fingerprint

Diclofenac
Analgesia
Headache
Ambulatory Surgical Procedures
Postoperative Period
Pain
Craniotomy
Lidocaine
Epinephrine
Analgesics
Safety
Incidence
Neoplasms

Keywords

  • Postcraniotomy headache
  • Preemptive analgesia

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Simon, É., Bánk, J., Gál, J., Siró, P., Novák, L., Fülesdi, B., & Molnár, C. (2012). Administration of preemptive analgesia by diclofenac to prevent acute postcraniotomy headache. Ideggyógyászati szemle, 65(9-10), 302-306.

Administration of preemptive analgesia by diclofenac to prevent acute postcraniotomy headache. / Simon, Éva; Bánk, Judit; Gál, Judit; Siró, Péter; Novák, Lászĺo; Fülesdi, B.; Molnár, Csilla.

In: Ideggyógyászati szemle, Vol. 65, No. 9-10, 30.09.2012, p. 302-306.

Research output: Contribution to journalArticle

Simon, É, Bánk, J, Gál, J, Siró, P, Novák, L, Fülesdi, B & Molnár, C 2012, 'Administration of preemptive analgesia by diclofenac to prevent acute postcraniotomy headache', Ideggyógyászati szemle, vol. 65, no. 9-10, pp. 302-306.
Simon, Éva ; Bánk, Judit ; Gál, Judit ; Siró, Péter ; Novák, Lászĺo ; Fülesdi, B. ; Molnár, Csilla. / Administration of preemptive analgesia by diclofenac to prevent acute postcraniotomy headache. In: Ideggyógyászati szemle. 2012 ; Vol. 65, No. 9-10. pp. 302-306.
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