Idarucizumab alkalmazása dabigatranterápia melletti spontán intracerebral vérzésben

Translated title of the contribution: Administration of idarucizumab in spontaneous intracerebral hemorrhage under dabigatran-Therapy

D. Bereczki, Géza Szilágyi, Llona Kakuk, Zoltán Szakács, Zsolt May

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Introduction -Among antidotes in development for reversal of novel oral anticoagulants, dabigatran-specific idaruci- zumab was the first one to reach the market. Case presentation - We present the first Hungarian case of intracerebral hemorrhage under treatment with dabigat- ran, where idarucizumab was administered to suspend anticoagulation. Discussion - Our report is concordant with prior publications, confirming the efficacy of the antidote in reversing the effect of dabigatran, and thus, preventing intracerebral hematoma progression in the acute phase. Conclusion - Since there is no proven alternative to idarucizumab, conducting randomized clinical trials would be unethical. Therefore, besides case reports, positive results of prospective studies could help us revise therapeutic guidelines, and thus, improve the prognosis of dabigatran-Associated intracerebral hemorrhages.

Translated title of the contributionAdministration of idarucizumab in spontaneous intracerebral hemorrhage under dabigatran-Therapy
Original languageHungarian
Pages (from-to)349-353
Number of pages5
JournalIdeggyogyaszati Szemle
Volume70
Issue number9-10
DOIs
Publication statusPublished - Sep 30 2017

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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