Administration of antisomatotrop serum in diabetes mellitus

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The effect of antisomatotrop serum (ASS), raised in horse against human growth hormone, on the carbohydrate metabolism of diabetics was investigated. Among the 8 diabetic patients treated so far 2 had GH secreting pituitary adenoma, 2 insulin-dependent, and 4 others adult onset diabetes mellitus. The glucose tolerance curve improved in all but one patient. The effect lasted for 2-4 weeks. Because of this short time of efficiency, the place of ASS in the definite treatment of diabetes mellitus cannot been judged so far, however, its administration in diabetic retinopathy seems to be advantageous.

Original languageEnglish
Pages (from-to)87-94
Number of pages8
Issue number1
Publication statusPublished - Jan 1 1981


ASJC Scopus subject areas

  • Endocrinology

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