Adenovirus infection in lambs. II. Experimental infection of lambs.

V. Palya, S. Belák, V. Pálfi

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Adenovirus strain GY/14 isolated during a natural outbreak was used in experimental infection. Three weeks old lambs responded with temperature rise, respiratory symptoms and diarrhoea to the infection. Infection spread to a contact animal, too. Reisolation of the virus was successful from the nasal discharge and feces from the 3rd to 10th, and the 3rd to 5th day following infection, respectively. In the killed experimental animals the pathological and histological changes observed were similar to those observed in natural cases. On comparing the natural outbreaks with the experimental infection the only difference appeared in the severity of the changes. Following the experimental infection characteristic nuclear inclusions appeared in the nasal and bronchiolar epithelium, in the alveolar septal cells and in the reticular cells of the lymph nodes. Epizootiologic observations and experimental results confirm the assumption that our adenovirus strains isolated from natural cases are pathogenic for lambs.

Original languageEnglish
Pages (from-to)529-541
Number of pages13
JournalZentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B
Volume24
Issue number7
Publication statusPublished - Aug 1977

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Adenoviridae Infections
lambs
Infection
infection
Adenoviridae
Disease Outbreaks
nuclear inclusions
Alveolar Epithelial Cells
Intranuclear Inclusion Bodies
Nasal Mucosa
Nose
Feces
signs and symptoms (animals and humans)
lymph nodes
laboratory animals
Adenoviridae infections
Diarrhea
diarrhea
epithelium
feces

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Adenovirus infection in lambs. II. Experimental infection of lambs. / Palya, V.; Belák, S.; Pálfi, V.

In: Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B, Vol. 24, No. 7, 08.1977, p. 529-541.

Research output: Contribution to journalArticle

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