Adenovirus gastroenteritis in Hungary, 2003-2006

K. Bányai, P. Kisfali, Á Bogdán, V. Martella, B. Melegh, D. Erdman, G. Szucs

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The incidence and type distribution of enteric human adenoviruses (HAds) among diarrheic children in south-western Hungary was investigated from 2003 through 2006. Laboratory studies were conducted using commercial antigen detection tests (latex agglutination or immunochromatography), polymerase chain reaction (PCR) amplification, single-strand conformation polymorphism, and sequencing and phylogenetic analysis of a conservative region of the HAd hexon gene. The overall rate of HAd infection in childhood gastroenteritis cases during the 4-year study was 8.1%, with a gradual decrease in detection rates from 11.7% in 2003 to 5.7% in 2006. Molecular studies of a subset of HAd-positive samples found that enteric HAd type 40 strains were identified only in 2003 and 2004, while HAd type 41 strains were identified throughout the 4-year study. Higher detection rates of non-enteric HAds was documented during the first half of the study period when latex agglutination was used in our laboratory for detection. Our study suggests that the choice of diagnostic method may profoundly influence the epidemiologic picture and disease burden attributed to enteric HAd infections.

Original languageEnglish
Pages (from-to)997-999
Number of pages3
JournalEuropean Journal of Clinical Microbiology and Infectious Diseases
Volume28
Issue number8
DOIs
Publication statusPublished - Aug 2009

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Human Adenoviruses
Hungary
Gastroenteritis
Adenoviridae
Immunochromatography
Latex Fixation Tests
Agglutination
Latex
Infection
Antigens
Polymerase Chain Reaction
Incidence
Genes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Adenovirus gastroenteritis in Hungary, 2003-2006. / Bányai, K.; Kisfali, P.; Bogdán, Á; Martella, V.; Melegh, B.; Erdman, D.; Szucs, G.

In: European Journal of Clinical Microbiology and Infectious Diseases, Vol. 28, No. 8, 08.2009, p. 997-999.

Research output: Contribution to journalArticle

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AU - Szucs, G.

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