Adenomatous leydig cell hyperplasia of the testicle remnant after subtotal orchidectomy in the rat

F. Szarvas, S. Karcsú, I. Tóth, M. Gálfi, J. Julesz, I. Faredin

Research output: Contribution to journalArticle

Abstract

Subtotal orchidectomy is a suitable method to induce adenomatous Leydig cell hyperplasia in the testicular remnant without irradiation or toxic chemicals. Very expressed hyperplasia of the smooth endoplasmic reticulum was detectable electronmicroscopically in the newly formed Leydig cells. The activity of Δ5-3β-hydroxysteroid dehydrogenase in the homogenate of the testicular remnant was found considerably elevated. These observations suggest a steroidogenetic activity of the proliferating Leydig cells.

Original languageEnglish
Pages (from-to)196-200
Number of pages5
JournalEndocrine Pathology
Volume4
Issue number4
DOIs
Publication statusPublished - Dec 1 1993

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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