Acute-phase response in dairy cows with acute postpartum metritis

J. Hirvonen, G. Huszenicza, M. Kulcsár, S. Pyörälä

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

The diagnostic value of 2 plasma acute-phase proteins, haptoglobin and α1-acid glycoprotein, and plasma N-acetyl-β-D-glucosaminidase enzyme activity were studied in 29 newly calved dairy cows. Nineteen had developed acute metritis with putrid vaginal discharge within 2 wk after calving; 10 were clinically healthy controls. Plasma haptoglobin concentration remained low in most cows with acute postpartum metritis. Only the 3 most severely affected cows exhibited a strong haptoglobin response. These were later culled due to poor condition and reduced fertility. This suggests that in acute uterine infection a highly increased haptoglobin concentration indicates poor prognosis for repeat conception. Plasma α1-acid glycoprotein concentration increased in acute postpartum metritis, the response pattern being less prominent than that for haptoglobin. The α1-acid glycoprotein concentrations did not correlate with severity of disease, and, consequently, the capacity of α1-acid glycoprotein in differentiating genital infections was relatively poor. The highest α1-acid glycoprotein concentrations were detected in cows with retained placenta and/or dystocia. Plasma N-acetyl-β- D-glucosaminidase activity levels did not differ between the cows with acute postpartum metritis and healthy control cows.

Original languageEnglish
Pages (from-to)1071-1083
Number of pages13
JournalTheriogenology
Volume51
Issue number6
Publication statusPublished - Apr 15 1999

Fingerprint

Acute-Phase Reaction
Haptoglobins
haptoglobins
endometritis
Postpartum Period
glycoproteins
Glycoproteins
dairy cows
cows
Acids
acids
Hexosaminidases
4 alpha-glucanotransferase
Retained Placenta
Vaginal Discharge
Dystocia
retained placenta
acute phase proteins
Acute-Phase Proteins
dystocia

Keywords

  • α-acid glycoprotein
  • Acute-phase response
  • Cattle
  • Haptoglobin
  • Metritis

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Acute-phase response in dairy cows with acute postpartum metritis. / Hirvonen, J.; Huszenicza, G.; Kulcsár, M.; Pyörälä, S.

In: Theriogenology, Vol. 51, No. 6, 15.04.1999, p. 1071-1083.

Research output: Contribution to journalArticle

Hirvonen, J. ; Huszenicza, G. ; Kulcsár, M. ; Pyörälä, S. / Acute-phase response in dairy cows with acute postpartum metritis. In: Theriogenology. 1999 ; Vol. 51, No. 6. pp. 1071-1083.
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