Active percolation analysis of pyramidal neurons of somatosensory cortex: A comparison of wild type and p21H-RasVal12 transgenic mice

Luciano D A Fontoura Costa, Marconi Soares Barbosa, Andreas Schierwagen, A. Alpár, Ulrich Gärtner, Thomas Arendt

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

This article describes the investigation of morphological variations among two sets of neuronal cells, namely a control group of wild type rat cells and a group of cells of a trangenic line. Special attention is given to singular points in the neuronal structure, namely the branching points and extremities of the dendritic processes. The characterization of the spatial distribution of such points is obtained by using a recently reported morphological technique based on forced percolation and window-size compensation, which is particularly suited to the analysis of scattered points, presenting several coexisting densities. Different dispersions were identified in our statistical analysis, suggesting that the transgenic line of neurons is characterized by a more pronounced morphological variation. A classification scheme based on a canonical discriminant function was also considered in order to identify the morphological differences.

Original languageEnglish
Pages (from-to)655-667
Number of pages13
JournalInternational Journal of Modern Physics C
Volume16
Issue number4
DOIs
Publication statusPublished - Apr 2005

Fingerprint

Transgenic Mice
cortexes
Cortex
neurons
Dispersions
Spatial distribution
Neurons
mice
Rats
Neuron
Statistical methods
Cell
cells
Discriminant Function
Line
Singular Point
Spatial Distribution
statistical analysis
rats
Statistical Analysis

Keywords

  • Density analysis
  • Neuromorphometry
  • Neuronal shape
  • Percolation
  • Phase transition

ASJC Scopus subject areas

  • Computer Science Applications
  • Computational Theory and Mathematics
  • Physics and Astronomy(all)
  • Statistical and Nonlinear Physics
  • Mathematical Physics

Cite this

Active percolation analysis of pyramidal neurons of somatosensory cortex : A comparison of wild type and p21H-RasVal12 transgenic mice. / Costa, Luciano D A Fontoura; Barbosa, Marconi Soares; Schierwagen, Andreas; Alpár, A.; Gärtner, Ulrich; Arendt, Thomas.

In: International Journal of Modern Physics C, Vol. 16, No. 4, 04.2005, p. 655-667.

Research output: Contribution to journalArticle

Costa, Luciano D A Fontoura ; Barbosa, Marconi Soares ; Schierwagen, Andreas ; Alpár, A. ; Gärtner, Ulrich ; Arendt, Thomas. / Active percolation analysis of pyramidal neurons of somatosensory cortex : A comparison of wild type and p21H-RasVal12 transgenic mice. In: International Journal of Modern Physics C. 2005 ; Vol. 16, No. 4. pp. 655-667.
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