Activation energies of fragmentations of disaccharides by tandem mass spectrometry

Ákos Kuki, Lajos Nagy, Katalin E. Szabó, Borbála Antal, M. Zsuga, S. Kéki

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A simple multiple collision model for collision induced dissociation (CID) in quadrupole was applied for the estimation of the activation energy (E o) of the fragmentation processes for lithiated and trifluoroacetated disaccharides, such as maltose, cellobiose, isomaltose, gentiobiose, and trehalose. The internal energy-dependent rate constants k(Eint) were calculated using the Rice-Ramsperger-Kassel-Marcus (RRKM) or the Rice-Ramsperger-Kassel (RRK) theory. The Eo values were estimated by fitting the calculated survival yield (SY) curves to the experimental ones. The calculated Eo values of the fragmentation processes for lithiated disaccharides were in the range of 1.4-1.7 eV, and were found to increase in the order trehalose <maltose <isomaltose <cellobiose <gentiobiose. [Figure not available: see fulltext.]

Original languageEnglish
Pages (from-to)439-443
Number of pages5
JournalJournal of the American Society for Mass Spectrometry
Volume25
Issue number3
DOIs
Publication statusPublished - Mar 2014

Fingerprint

Isomaltose
Cellobiose
Trehalose
Maltose
Disaccharides
Tandem Mass Spectrometry
Mass spectrometry
Activation energy
Rate constants
gentiobiose
Oryza

Keywords

  • Collision-induced dissociation
  • Disaccharides
  • Multiple collisions
  • RRK and RRKM model
  • Tandem mass spectrometry

ASJC Scopus subject areas

  • Structural Biology
  • Spectroscopy

Cite this

Activation energies of fragmentations of disaccharides by tandem mass spectrometry. / Kuki, Ákos; Nagy, Lajos; Szabó, Katalin E.; Antal, Borbála; Zsuga, M.; Kéki, S.

In: Journal of the American Society for Mass Spectrometry, Vol. 25, No. 3, 03.2014, p. 439-443.

Research output: Contribution to journalArticle

Kuki, Ákos ; Nagy, Lajos ; Szabó, Katalin E. ; Antal, Borbála ; Zsuga, M. ; Kéki, S. / Activation energies of fragmentations of disaccharides by tandem mass spectrometry. In: Journal of the American Society for Mass Spectrometry. 2014 ; Vol. 25, No. 3. pp. 439-443.
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