Actions of methionine enkephalin and morphine on single neuronal activity in Helix pomatia L.

G. B. Stefano, K. S. -Rózsa, L. Hiripi

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

1. Methionine enkephalin and morphine accelerated the firing frequency of the cells in the right parietal (RPa2) and visceral (V) ganglia of Helix pomatia L. The effect of both agents was blocked by naloxone. 2. Naloxone blocked the inhibitory effect caused by dopamine application to the RPa2 cell. 3. Dopamine had a stimulatory effect on the neurosecretory cell (NS) which was not altered by naloxone pretreatments. 4. Naloxone specificity may be extended to a type of dopamine receptor. 5. In Helix pomatia L. an opiate receptor with similar pharmacological properties to that reported in mammals exists.

Original languageEnglish
Pages (from-to)193-198
Number of pages6
JournalComparative Biochemistry and Physiology. Part C, Comparative
Volume66
Issue number2
DOIs
Publication statusPublished - 1980

ASJC Scopus subject areas

  • Immunology
  • Pharmacology

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