Acovulparine, a new norditerpene alkaloid from Aconitum vulparia

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Acovulparine (= 1α,6β,7R,8β,14α,16β)-4- (hydroxymethyl)-1,6,14,16-tetramethoxyaconit-19-ene-7,8-diol: 1), a new norditerpene alkaloid, was isolated from the MeOH extract of the whole plants of Aconitum vulparia REICHENB., together with the known compounds lycoctonine (2) and delcosine (3). The structures were established by HR-EI-MS and advanced 2D-NMR, including 1H-NMR, JMOD, 1H,1H-COSY, HSQC, and HMBC experiments. Acovulparine was found to contain the rare C(19)=N azomethine group.

Original languageEnglish
Pages (from-to)2125-2130
Number of pages6
JournalHelvetica Chimica Acta
Volume87
Issue number8
DOIs
Publication statusPublished - Oct 4 2004

    Fingerprint

ASJC Scopus subject areas

  • Catalysis
  • Biochemistry
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Cite this