Acetylcholinesterase (AchE) activity of lymphocytes in chronic lymphoid leukemia (CLL)

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10 Citations (Scopus)

Abstract

The specific AchE (EC 3.1.1.7) activity of lymphocytes from the peripheral blood of normal donors was determined. On Leukopak filter the isolated T lymphocytes showed activity, whereas in stepwise Percoll gradient, population TLD displayed enzyme activity. The THD and B cells were inactive. [Szelényi J. G., Bartha E. & Hollán S. R. (1982) Br. J. Haemat. 50, 241]. A mixed cell population derived from CLL patients had significantly lower enzyme activity than normal. With the progress of B-cell proliferation AchE activity decreased in parallel with the number of T cells. The sp. act. of TLD population isolated from CLL patients was the same as that of normal donors whereas their B cells were inactive.

Original languageEnglish
Pages (from-to)861-864
Number of pages4
JournalLeukemia Research
Volume6
Issue number6
DOIs
Publication statusPublished - 1982

Keywords

  • B populations
  • Chronic lymphoid leukemia
  • T
  • T
  • acetylcholinesterase activity

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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