Acetylcholine-releasing effect of gastrin and related polypeptides

E. S. Vizi, G. Bertaccini, M. Impicciatore, J. Knoll

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

The effect of gastrin and related polypeptides on acetylcholine release from the Auerbach plexus of guinea pig longitudinal muscle strip were studied. Gastrin, octapeptide amide of cholecystokinin, pentagastrin and caerulein released acetylcholine from longitudinal muscle strip. Noradrenaline and tetrodotoxin prevented both release of acetylcholine and contraction of the intestine produced by gastrin and related polypeptides.

Original languageEnglish
Pages (from-to)175-178
Number of pages4
JournalEuropean Journal of Pharmacology
Volume17
Issue number1
DOIs
Publication statusPublished - Jan 1972

Keywords

  • Acetylcholine release
  • Gastrin
  • Noradrenaline
  • Polypeptides

ASJC Scopus subject areas

  • Pharmacology

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