Accuracy of macular ganglion-cell complex thickness to total retina thickness ratio to detect glaucoma in white Europeans

G. Holló, Farzaneh Naghizadeh, P. Vargha

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Purpose: The aim of this study was to evaluate the diagnostic accuracy of macular ganglion-cell complex (GCC) thickness to total retinal thickness ratio (G/T ratio), a parameter found particularly accurate in Japanese eyes to detect glaucoma and recently proposed for the RTVue-100 Fourier-domain optical coherence tomography (RTVue-100 OCT), and to compare the diagnostic accuracy of this parameter to that of parameters provided by the instrument software in European eyes.

Methods: Retinal nerve fiber layer thickness (RNFLT) and macular GCC thickness parameters of 1 randomly selected eye of 177 white European patients (50 healthy, 28 ocular hypertensive, 33 preperimetric glaucoma, and 66 perimetric glaucoma eyes) were measured with an RTVue-100 OCT.

Results: The RNFLT and GCC parameter values of the healthy group were significantly higher than those of the various other groups (P

Conclusions: In contrast to Japanese eyes, in white Europeans G/T ratio does not improve separation of glaucomatous and healthy eyes.

Original languageEnglish
Pages (from-to)e132-e137
JournalJournal of Glaucoma
Volume23
Issue number8
DOIs
Publication statusPublished - Dec 10 2014

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Ganglia
Glaucoma
Retina
Optical Coherence Tomography
Nerve Fibers
Software

Keywords

  • G/T ratio
  • Ganglion-cell complex
  • Glaucoma
  • Retinal nerve fiber layer
  • RTVue Fourierdomain OCT
  • Spectral-domain optical coherence tomography

ASJC Scopus subject areas

  • Ophthalmology
  • Medicine(all)

Cite this

Accuracy of macular ganglion-cell complex thickness to total retina thickness ratio to detect glaucoma in white Europeans. / Holló, G.; Naghizadeh, Farzaneh; Vargha, P.

In: Journal of Glaucoma, Vol. 23, No. 8, 10.12.2014, p. e132-e137.

Research output: Contribution to journalArticle

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