A weighted patient specific electromechanical model of the heart

Sándor M. Szilágyi, László Szilágyi, David Iclǎnzan, Zoltán Benyó

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper presents a patient specific deformable heart model that involves the known electric and mechanic properties of the cardiac cells and tissue. The accuracy and efficiency of the algorithm was tested for anisotropic and inhomogeneous 3D domains using ten Tusscher's and Nygen's cardiac cell models. During propagation of depolarization wave, the kinetic, compositional and rotational anisotropy is included in the tissue, organ and torso model. The applied patient specific parameters were determined by an evolutionary computation method. An intensive parameter reduction was performed using the abstract formulation of the searching space. This patient specific parameter representation enables the adjustment of deformable model parameters in real-time. The validation process was performed using measured ECG and ultrasound image records that were compared with simulated signals and shapes using an abstract, parameterized evaluation criterion.

Original languageEnglish
Title of host publication7th IFAC Symposium on Modelling and Control in Biomedical Systems (including Biological Systems) MCBMS'09 - Proceedings
Pages270-275
Number of pages6
EditionPART 1
DOIs
Publication statusPublished - Dec 1 2009
Event7th IFAC Symposium on Modelling and Control in Biomedical Systems (including Biological Systems) MCBMS'09 - Aalborg, Denmark
Duration: Aug 12 2009Aug 14 2009

Publication series

NameIFAC Proceedings Volumes (IFAC-PapersOnline)
NumberPART 1
Volume7
ISSN (Print)1474-6670

Other

Other7th IFAC Symposium on Modelling and Control in Biomedical Systems (including Biological Systems) MCBMS'09
CountryDenmark
CityAalborg
Period8/12/098/14/09

    Fingerprint

Keywords

  • Active appearance motion model
  • Electro-mechanical heart model
  • Evolutionary computation
  • Parameter reduction
  • Patient specific analysis

ASJC Scopus subject areas

  • Control and Systems Engineering

Cite this

Szilágyi, S. M., Szilágyi, L., Iclǎnzan, D., & Benyó, Z. (2009). A weighted patient specific electromechanical model of the heart. In 7th IFAC Symposium on Modelling and Control in Biomedical Systems (including Biological Systems) MCBMS'09 - Proceedings (PART 1 ed., pp. 270-275). (IFAC Proceedings Volumes (IFAC-PapersOnline); Vol. 7, No. PART 1). https://doi.org/10.3182/20090812-3-DK-2006.0079