A survey of ATRIPLA use in clinical practice as first-line therapy in HIV-positive persons in Europe

for EuroSIDA in EuroCOORD

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

ATRIPLA is licensed for use only in HIV-positive persons whose viral loads <50 for ≥3 months. We investigated the use of ATRIPLA as first-line antiretroviral therapy (ART) in EuroSIDA using a web-based survey performed in Autumn 2012. 96/112 clinics (85.7 %) completed the survey. Recommendations when initiating first-line ART was TRUVADA plus efavirenz in 36 (37.5 %), ATRIPLA in 35 (36.5 %), a different first-line regimen in 12 clinics (12.5 %), and no recommendation in 7 clinics (7.3 %). ATRIPLA was commonest in Northern (15/21 clinics; 71.4 %), and least common in Eastern Europe (2/31 clinics; 6.5 %; p < 0.0001). Over one-third of the participating clinics in this survey were using ATRIPLA as first-line antiretroviral therapy, despite EMA recommendations.

Original languageEnglish
Pages (from-to)757-762
Number of pages6
JournalInfection
Volume42
Issue number4
DOIs
Publication statusPublished - Aug 1 2014

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'A survey of ATRIPLA use in clinical practice as first-line therapy in HIV-positive persons in Europe'. Together they form a unique fingerprint.

  • Cite this