A study on the phosphorylation of indole, imidazole, carbazole, and phenothiazine derivatives

Mátyás Milen, Péter Ábrányi-Balogh, György Balogh, L. Drahos, G. Keglevich

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

N-Heterocycles including indolecarbaldehyde, substituted benzimidazoles, and methylimidazole could be efficiently phosphorylated by diethyl chlorophosphate at room temperature in different solvents using alkali carbonate or triethylamine as the base. However, the phosphorylation of N-heterocycles with a lower reactivity at the NH function, such as carbazole and phenothiazine, could not be conducted to complete conversion under the conditions applied.

Original languageEnglish
Pages (from-to)1091-1100
Number of pages10
JournalPhosphorus, Sulfur and Silicon and Related Elements
Volume187
Issue number9
DOIs
Publication statusPublished - Sep 1 2012

Fingerprint

Benzimidazoles
Phosphorylation
Carbonates
Alkalies
Derivatives
Temperature
triethylamine
imidazole
indole
carbazole
diethylchlorophosphate
phenothiazine

Keywords

  • carbazole
  • imidazoles
  • indoles
  • N-heterocycles
  • phenothiazine
  • phosphorylation

ASJC Scopus subject areas

  • Inorganic Chemistry
  • Organic Chemistry
  • Biochemistry

Cite this

A study on the phosphorylation of indole, imidazole, carbazole, and phenothiazine derivatives. / Milen, Mátyás; Ábrányi-Balogh, Péter; Balogh, György; Drahos, L.; Keglevich, G.

In: Phosphorus, Sulfur and Silicon and Related Elements, Vol. 187, No. 9, 01.09.2012, p. 1091-1100.

Research output: Contribution to journalArticle

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