A study of the liver glucocorticoid receptor binding capacity in newborn rat

G. Csaba, Ágnes Inczefi-Gonda

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1 Citation (Scopus)

Abstract

The binding capacity of newborn and adult rat liver glucocorticoid receptors was compared, using receptor kinetic analysis. Neonatal receptors have (non-significantly) lower affinity and significantly less density to dexamethasone than adult ones. However, the neonatal binding is specific and there is no qualitative difference from the adult one.

Original languageEnglish
Pages (from-to)139-143
Number of pages5
JournalActa physiologica Hungarica
Volume87
Issue number2
Publication statusPublished - Dec 1 2000

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Keywords

  • Binding capacity
  • Dexamethasone
  • Glucocorticoid receptors
  • Neonatal receptors
  • Rat
  • Receptor kinetic analysis

ASJC Scopus subject areas

  • Physiology (medical)

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