A solution thermodynamic study of the Cu(II) and Zn(II) complexes of EBTA: X-ray crystal structure of the dimeric complex [Cu2(EBTA)(H2O)3]2

Z. Baranyai, Gabriella Bombieri, Fiorella Meneghetti, Lorenzo Tei, Mauro Botta

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The copper(II) complex of the acyclic EBTA ligand (H4EBTA = 1,2-bis(2-aminoethoxy)benzene-N,N,N′,N′-tetraacetic acid) has been prepared and characterized by X-ray analysis. The two copper ions of the dinuclear unit present the same distorted octahedral coordination polyhedra. The EBTA ligand is shared between two copper coordination centres, with the formation of centrosymmetric dimers, which are linked in a supramolecular tridimensional structure via additional interactions through the coordinated waters molecules with adjacent carboxylic oxygen atoms. The stability and protonation constants of EBTA with Cu(II) and Zn(II) ions indicate a higher stability of these complexes with respect to the corresponding complexes with the more flexible EGTA ligand (H4EGTA = ethyleneglycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid). On the other hand, the lower stability of [Gd(EBTA)]- than [Gd(EGTA)]- results in a decreased overall selectivity (lower Ksel) of EBTA towards Gd(III) and suggests that this complex may undergoes transmetallation reactions under physiological conditions.

Original languageEnglish
Pages (from-to)2259-2264
Number of pages6
JournalInorganica Chimica Acta
Volume362
Issue number7
DOIs
Publication statusPublished - May 15 2009

Fingerprint

Copper
Crystal structure
Egtazic Acid
Ligands
Thermodynamics
X rays
copper
thermodynamics
ligands
crystal structure
Ions
acids
Acids
x rays
Protonation
X ray analysis
Benzene
polyhedrons
Dimers
oxygen atoms

Keywords

  • Acyclic ligands
  • Cu(II) complex
  • Thermodynamic stability
  • X-ray crystal structure

ASJC Scopus subject areas

  • Inorganic Chemistry
  • Physical and Theoretical Chemistry
  • Materials Chemistry

Cite this

A solution thermodynamic study of the Cu(II) and Zn(II) complexes of EBTA : X-ray crystal structure of the dimeric complex [Cu2(EBTA)(H2O)3]2. / Baranyai, Z.; Bombieri, Gabriella; Meneghetti, Fiorella; Tei, Lorenzo; Botta, Mauro.

In: Inorganica Chimica Acta, Vol. 362, No. 7, 15.05.2009, p. 2259-2264.

Research output: Contribution to journalArticle

Baranyai, Z. ; Bombieri, Gabriella ; Meneghetti, Fiorella ; Tei, Lorenzo ; Botta, Mauro. / A solution thermodynamic study of the Cu(II) and Zn(II) complexes of EBTA : X-ray crystal structure of the dimeric complex [Cu2(EBTA)(H2O)3]2. In: Inorganica Chimica Acta. 2009 ; Vol. 362, No. 7. pp. 2259-2264.
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AB - The copper(II) complex of the acyclic EBTA ligand (H4EBTA = 1,2-bis(2-aminoethoxy)benzene-N,N,N′,N′-tetraacetic acid) has been prepared and characterized by X-ray analysis. The two copper ions of the dinuclear unit present the same distorted octahedral coordination polyhedra. The EBTA ligand is shared between two copper coordination centres, with the formation of centrosymmetric dimers, which are linked in a supramolecular tridimensional structure via additional interactions through the coordinated waters molecules with adjacent carboxylic oxygen atoms. The stability and protonation constants of EBTA with Cu(II) and Zn(II) ions indicate a higher stability of these complexes with respect to the corresponding complexes with the more flexible EGTA ligand (H4EGTA = ethyleneglycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid). On the other hand, the lower stability of [Gd(EBTA)]- than [Gd(EGTA)]- results in a decreased overall selectivity (lower Ksel) of EBTA towards Gd(III) and suggests that this complex may undergoes transmetallation reactions under physiological conditions.

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