A simple microassay for interleukin-2 activity

Istvan Ando, Peter C.L. Beverley

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A simple in vitro assay is described to quantitate human interleukin-2 (IL-2). It is based on the 'spontaneous' activation of human peripheral T cells in tissue culture and the subsequent expression of the IL-2 receptor. The results obtained with this assay agree with those of assays which utilise IL-2 dependent T cell clones. The method is highly sensitive, reproducible and easy to perform.

Original languageEnglish
Pages (from-to)133-137
Number of pages5
JournalJournal of Immunological Methods
Volume96
Issue number1
DOIs
Publication statusPublished - Jan 26 1987

Keywords

  • Bioassay
  • Interleukin-2
  • T cell
  • T cell activation

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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