A simple method for the determination of capacity factor on solid-phase extraction cartridges. I

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In this paper a simple experimental method for the rapid determination of capacity factors of phenolic compounds on off-line solid-phase extraction cartridges is described. A model solution of the analytes is brought into equilibrium with the SPE cartridge by recycling in a closed loop. The capacity factors are calculated from the adsorbed amounts which can be determined by a chromotographic method. The method is shown to give comparable results with those of the breakthrough experiments. The simplicity of the experimental methods of the well as the low cost and unattended operation offer a viable alternative to the conventional methods of the determination of capacity factors on SPE cartridges. Practical limitations of the proposed method are also considered.

Original languageEnglish
Pages (from-to)217-225
Number of pages9
JournalJournal of Chromatography A
Issue number2
Publication statusPublished - Feb 24 1995


ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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