Through the addition of 2 moles of formaldehyde to l-methyl-6,7-dimethoxy- and 6,7-diethoxy-3,4-dihydroisoquinoline, the corresponding 1-[bis(hydroxymethyl)methyl]-6,7-dialkoxy-3,4-dihydroisoquinolines (3a,b) were prepared, which were then reduced to the 1,3,3′-trifunctional tetrahydroisoquinoline aminoalcohol synthons (5a,b).
|Number of pages||5|
|Publication status||Published - Aug 1 1986|
ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry