A simple allogeneic test system for the study of antibody-dependent cellular cytotoxicity (ADCC) in man.

I. Láng, B. Fekete, P. Gergely, G. Petrányi

Research output: Contribution to journalArticle

Abstract

A simple allogeneic test system for the study of ADCC activity of human mononuclear peripheral blood leucocytes (MPBL) is presented. The test uses human Rh-positive erythrocytes as target cells coated with specific human IgG antibody. The effector function of human MPBL is demonstrated after depletion of most of the monocytes and B lymphocytes on nylon wool column. The test system seems to be useful in the clinical study of ADCC activity in man.

Original languageEnglish
Pages (from-to)85-91
Number of pages7
JournalHaematologia
Volume11
Issue number1-2
Publication statusPublished - 1977

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Antibodies
Leukocytes
Wool
Nylons
Human Activities
Monocytes
B-Lymphocytes
Immunoglobulin G
Erythrocytes
Clinical Studies

ASJC Scopus subject areas

  • Hematology

Cite this

A simple allogeneic test system for the study of antibody-dependent cellular cytotoxicity (ADCC) in man. / Láng, I.; Fekete, B.; Gergely, P.; Petrányi, G.

In: Haematologia, Vol. 11, No. 1-2, 1977, p. 85-91.

Research output: Contribution to journalArticle

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