A short, enantiospecific synthesis of a protected seco acid precursor to (R,R)-(-) pyrenophorin

Robert V. Hoffman, T. Patonay, Naresh K. Nayyar, Junhua Tao

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Described herein is a four-step enantiospecific synthesis of a protected seco acid precursor of (R,R)-(-)-pyrenophorin in 23% yield from a chiral β-ketoester 3, which can be prepared in one step from ethyl acetoacetate by a standard procedure.

Original languageEnglish
Pages (from-to)2381-2384
Number of pages4
JournalTetrahedron Letters
Volume37
Issue number14
DOIs
Publication statusPublished - Apr 1 1996

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Acids
ethyl acetoacetate
pyrenophorin

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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A short, enantiospecific synthesis of a protected seco acid precursor to (R,R)-(-) pyrenophorin. / Hoffman, Robert V.; Patonay, T.; Nayyar, Naresh K.; Tao, Junhua.

In: Tetrahedron Letters, Vol. 37, No. 14, 01.04.1996, p. 2381-2384.

Research output: Contribution to journalArticle

Hoffman, Robert V. ; Patonay, T. ; Nayyar, Naresh K. ; Tao, Junhua. / A short, enantiospecific synthesis of a protected seco acid precursor to (R,R)-(-) pyrenophorin. In: Tetrahedron Letters. 1996 ; Vol. 37, No. 14. pp. 2381-2384.
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