A coxibok hatásai és mellékhatásai

Translated title of the contribution: A reumatológiai gyakorlatban

Research output: Contribution to journalReview article

Abstract

The author reviews the various tools of pain control in rheumatic disorders, with special attention to the pharmacological modalities, focusing on the use of cyclo-oxygenase inhibitors (coxibs). The new pain control drugs have different side-effect profiles, and even though these are more favourable than those of the traditional drugs, not all of them meet the strict safety requirements. The new drugs that are available in Hungary have a lower gastrointestinal side effect risk than the traditional nonsteroidal anti-inflammatory drugs, still with comparable effectiveness. The non-steroidal antiinflammatory drugs - including the selective cyclo-oxygenase inhibitors - increase the risk of cardiovascular disease, though to varying extent. When choosing a drug to control pain and inflammation in the diseases of the locomotor system, the physician should balance between the effectiveness and the most common side effects (gastrointestinal, cardiovascular).

Original languageHungarian
Pages (from-to)469-475
Number of pages7
JournalLege Artis Medicinae
Volume18
Issue number6-7
Publication statusPublished - Jul 1 2008

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ASJC Scopus subject areas

  • Medicine(all)

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