A retrospective dosimetric comparison of TG43 and a commercially available MBDCA for an APBI brachytherapy patient cohort

K. Zourari, T. Major, A. Herein, V. Peppa, C. Polgár, P. Papagiannis

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Purpose: To compare dosimetry using a contemporary model based dose calculation algorithm (MBDCA) following TG186 recommendations, and the conventional TG43 method in an 192Ir high dose rate (HDR) accelerated partial breast irradiation (APBI) patient cohort. Methods: Data of 38 APBI patients were studied. Dosimetry for the treatment plans was performed using both the TG43 and TG186 dose calculation methods of the Oncentra Brachy v4.4 treatment planning system (TPS). Analysis included indices of clinical interest for the planning target volume (PTV coverage, dose homogeneity, conformity) as well as dose volume histograms (DVH) for the breast, lung, heart, rib and skin. Significance testing of observed differences between TG43 and TG186 results was carried out and the effect of target location to these differences was studied. Results: Statistically significant differences were observed in the values of clinically relevant DVH parameters for the PTV and the organs at risk (OAR), except for the heart. Differences for the PTV are relatively small (

Original languageEnglish
Pages (from-to)669-676
Number of pages8
JournalPhysica Medica
Volume31
Issue number7
DOIs
Publication statusPublished - Nov 1 2015

Fingerprint

Brachytherapy
breast
Breast
dosage
irradiation
Organs at Risk
Ribs
histograms
dosimeters
planning
Lung
Skin
Therapeutics
recommendations
organs
lungs
homogeneity

Keywords

  • Accelerated partial breast irradiation
  • Dose homogeneity and conformity indices
  • Dosimetry
  • DVH analysis
  • Model-based dose calculation algorithms
  • Treatment planning

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging
  • Physics and Astronomy(all)

Cite this

A retrospective dosimetric comparison of TG43 and a commercially available MBDCA for an APBI brachytherapy patient cohort. / Zourari, K.; Major, T.; Herein, A.; Peppa, V.; Polgár, C.; Papagiannis, P.

In: Physica Medica, Vol. 31, No. 7, 01.11.2015, p. 669-676.

Research output: Contribution to journalArticle

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