Shapiro-szindróma, azaz a termoregulációs zavar ritka esete

Translated title of the contribution: A rare case of thermoregulation disorder: Shapiro syndrome

Szabó Júlia, Zádori Dénes, Varga Edina Tímea, L. Vécsei

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Anomalies of the corpus callosum are the most frequent malformations of the central nervous system. The triad of spontaneous periodic hypothermia and hyperhydrosis with the agenesis of corpus callosum is described as Shapiro syndrome. Shapiro syndrome is a very rare condition and it can occur in every age group. The presence of agenesis of corpus callosum is not a strict criteria of the syndrome; the most important presenting symptom is paroxysmal hypothermia. Although the definite cause of recurrent hypothermia is unknown, dysfunction of the hypothalamus is suspected. From therapeutic aspects, only supportive therapy is available. In this report the authors present the first Shapiro syndrome case diagnosed in Hungary. The main symptoms of the 21-year-old male patient were recurrent hyperhydrosis with hypothermia resulting in severe general malaise. The skull magnetic resonance imaging demonstrated agenesis of corpus callosum. The patient was treated with clonidine resulting in significant improvement of symptoms.

Original languageHungarian
Pages (from-to)275-278
Number of pages4
JournalOrvosi Hetilap
Volume157
Issue number7
DOIs
Publication statusPublished - Feb 1 2016

Fingerprint

Body Temperature Regulation
Agenesis of Corpus Callosum
Hypothermia
Hungary
Corpus Callosum
Clonidine
Skull
Hypothalamus
Central Nervous System
Age Groups
Magnetic Resonance Imaging
Shapiro syndrome
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Shapiro-szindróma, azaz a termoregulációs zavar ritka esete. / Júlia, Szabó; Dénes, Zádori; Tímea, Varga Edina; Vécsei, L.

In: Orvosi Hetilap, Vol. 157, No. 7, 01.02.2016, p. 275-278.

Research output: Contribution to journalArticle

Júlia, Szabó ; Dénes, Zádori ; Tímea, Varga Edina ; Vécsei, L. / Shapiro-szindróma, azaz a termoregulációs zavar ritka esete. In: Orvosi Hetilap. 2016 ; Vol. 157, No. 7. pp. 275-278.
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