A possible pathomechanism of the idiopathic cold contact urticaria.

S. Husz, I. Tóth-Kása, F. Obál, G. Jancsó

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Urtica is characterized by an erythematous wheal surrounded by a flare and is frequently caused by physical agents (e.g. cold). The exact mechanism and mediators involved in the mechanism of physical urticaria are not known. This study of the role of the neurogenic factors in cold urticaria showed, that local capsaicin treatment (desensitization) of the skin in patients with cold urticaria resulted in the abolition of whealing in response to cold. This result suggests that C-fibers might play an important role in the pathomechanism of idiopathic contact cold urticaria.

Original languageEnglish
Pages (from-to)209-215
Number of pages7
JournalActa physiologica Hungarica
Volume77
Issue number3-4
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Physiology (medical)

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