A novel technique with a flexible applicator for MRI-based brachytherapy of cervical cancer

J. Hadjiev, G. Antal, Z. Antalffy, P. Bogner, O. Ésik, I. Repa

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Purpose: To introduce a novel technique for magnetic resonance (MR)-based 3-dimensional planned high-dose rate intracervical brachytherapy (BT). Materials and methods: During 2002, 16 patients received external beam radiotherapy and BT as part of radiochemotherapy for cervical cancer. A special adjustable applicator device was designed and used for BT. The isodose distribution was calculated from MR images with the applicator in place. Results: The planning target volume coverage was adequate and the radiation burden on the organs at risk was within acceptable limits. Complete regression was achieved in two patients (12.5%), and partial regression in ten (62.5%) patients. The overall response rate for the complex treatment was 93.75%. In three cases the disease was considered to be stable. Conclusion: The MR-compatible, flexible applicator allows safe and reproducible cervical radiotherapy with no added discomfort or hazard for the patient.

Original languageEnglish
Pages (from-to)347-350
Number of pages4
JournalEuropean Journal of Gynaecological Oncology
Volume25
Issue number3
Publication statusPublished - 2004

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Brachytherapy
Uterine Cervical Neoplasms
Magnetic Resonance Spectroscopy
Radiotherapy
Organs at Risk
Chemoradiotherapy
Radiation
Equipment and Supplies
Therapeutics

Keywords

  • Adjustable applicator
  • Cervix
  • Dose distribution

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Oncology

Cite this

A novel technique with a flexible applicator for MRI-based brachytherapy of cervical cancer. / Hadjiev, J.; Antal, G.; Antalffy, Z.; Bogner, P.; Ésik, O.; Repa, I.

In: European Journal of Gynaecological Oncology, Vol. 25, No. 3, 2004, p. 347-350.

Research output: Contribution to journalArticle

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AU - Repa, I.

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