The reaction of (6-substituted 3-pyridazinyloxy)alkanols 2a-d, 3a-d and 14a-c with thionyl chloride is described. The 2-chloroalkylpyridazinones 5b-d, 6b-d and 15a-c were formed from 2b-d, 3b-d and 14a-c, respectively, while the 3-chloroalkoxypyridazines 7a and 8a were isolated from the reaction of 2a and 3a, respectively. It was shown by chemical and spectroscopic evidences that the rearrangement reaction followed an intramolecular process through bicyclic intermediates.
|Number of pages||11|
|Publication status||Published - Jan 1 1989|
ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry