A novel and convenient method for the synthesis of free 5′-thiol modified oligonucleotides

Z. Kupihár, G. Kovács, Z. Kele, Z. Darula, L. Kovács

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The synthesis of free 5′-thiol-modified oligonucleotides using a 4,4′,4″-trimethoxytrityl (TMTr)-protected linker and standard Poly-Pak™ purification has been described.

Original languageEnglish
Pages (from-to)1297-1299
Number of pages3
JournalNucleosides, Nucleotides and Nucleic Acids
Volume22
Issue number5-8
DOIs
Publication statusPublished - 2003

Fingerprint

Sulfhydryl Compounds
Oligonucleotides
Purification

Keywords

  • 5′-Thiol linker
  • Oligonucleotide conjugation
  • Phosphoramidite
  • TMTr removal

ASJC Scopus subject areas

  • Genetics
  • Biochemistry

Cite this

A novel and convenient method for the synthesis of free 5′-thiol modified oligonucleotides. / Kupihár, Z.; Kovács, G.; Kele, Z.; Darula, Z.; Kovács, L.

In: Nucleosides, Nucleotides and Nucleic Acids, Vol. 22, No. 5-8, 2003, p. 1297-1299.

Research output: Contribution to journalArticle

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