A new type of histidine regulatory mutant in Escherichia coli

L. Patthy, G. Dénes

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A histidine regulatory mutant was isolated from Escherichia coli K12. This mutant has some characteristic features, which are different from those of Salmonella typhimurium regulatory mutants: i/ normal colony morphology, normal growth even at 43°C. ii/ the level of histidine biosynthetic enzymes is temperature dependent, high /22-25 times the wild type/ levels being attained at high temperatures. Following a period of leucine starvation there is a burst of enzyme synthesis, when leucine is readded.

Original languageEnglish
Pages (from-to)1246-1251
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume43
Issue number6
DOIs
Publication statusPublished - Jun 18 1971

Fingerprint

Histidine
Leucine
Escherichia coli
Escherichia coli K12
Salmonella
Temperature
Enzymes
Salmonella typhimurium
Starvation
Growth

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

A new type of histidine regulatory mutant in Escherichia coli. / Patthy, L.; Dénes, G.

In: Biochemical and Biophysical Research Communications, Vol. 43, No. 6, 18.06.1971, p. 1246-1251.

Research output: Contribution to journalArticle

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