A new mixed acetal-type substitution pattern for α-cyclodextrin. Preparation of hexakis(3-O-benzyl)-α-cyclodextrin

A. Lipták, L. Jánossy, G. Batta, A. Borbás, J. Szejtli

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

α-CD was converted into hexakis[2,6-di-O-(methoxydimethyl)methyl]-α-CD by a proton-catalyzed reaction with 2-methoxypropene. Subsequent benzylation under Brimacombe conditions resulted in the fully protected compound, from which the acid-sensitive acetal groups were removed to obtain hexakis(3-O-benzyl)-α-cyclodextrin. The structure of all of the compounds synthesized was confirmed by 13C J-ECHO, COSY, HETCOR and HMBC NMR measurements.

Original languageEnglish
Pages (from-to)111-116
Number of pages6
JournalCarbohydrate Letters
Volume4
Issue number2
Publication statusPublished - 2000

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Acetals
Cyclodextrins
Protons
Acids
2-methoxypropene

Keywords

  • α-Cyclodextrin
  • Benzylation
  • Hexakis(3-O-benzyl)-α-CD
  • Mixed acetals

ASJC Scopus subject areas

  • Endocrinology

Cite this

A new mixed acetal-type substitution pattern for α-cyclodextrin. Preparation of hexakis(3-O-benzyl)-α-cyclodextrin. / Lipták, A.; Jánossy, L.; Batta, G.; Borbás, A.; Szejtli, J.

In: Carbohydrate Letters, Vol. 4, No. 2, 2000, p. 111-116.

Research output: Contribution to journalArticle

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AU - Jánossy, L.

AU - Batta, G.

AU - Borbás, A.

AU - Szejtli, J.

PY - 2000

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