A new method to extend dimercaptan or diamine chains with aminopropyl units using 3-bromo-N-tritylpropanamine

Krzysztof E. Krakowiak, Peter Huszthy, Jerald S. Bradshaw, Reed M. Izatt

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Dimercaptans and diamines react with 3-bromo-N-tritylpropanamine to give the corresponding N,N′-ditrityldithia and N,N′-ditritylpolyaza compounds in yields of 50-80%. The trityl protecting groups are readily removed in acid. These reactions make possible the synthesis of a number of new α-ω-diamino compounds needed for the synthesis of new dithiadiaza, di- and polyaza macrocyclic ligands.

Original languageEnglish
Pages (from-to)21-22
Number of pages2
JournalTetrahedron Letters
Volume32
Issue number1
DOIs
Publication statusPublished - Jan 1 1991

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ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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