A new endocardial "over-the-wire" or stylet-driven left ventricular lead: First clinical experience

Sue Ellery, Vince Paul, Guenther Prenner, Karlheinz Tscheliessnigg, Bela Merkely, Klaus Malinowski, Gerd Fröhlig, Florian Hintringer, Olaf Bosse, Paolo Diotallevi, Antonio P. Ravazzi, Horst Flathmann, Dejan Danilovic, Christina Unterberg-Buchwald

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14 Citations (Scopus)


Transvenous left ventricular (LV) leads are primarily inserted "over-the-wire" (OTW). However, a stylet-driven (SD) approach maybe a helpful alternative. A new polyurethane-coated, unipolar LV lead can be placed either by a stylet or a guide wire, which can be inserted into the lead body from both ends. The multicenter OVID study evaluates the clinical performance of this new steroid- and nonsteroid eluting lead. The primary endpoint is the LV lead implant success rate after identification of the coronary sinus (CS). Secondary endpoints include complication rate, short- and long-term lead characteristics, overall procedure and LV lead placement duration, total fluoroscopy time, and lead handling characteristics ratings. To date, 96 patients with heart failure (68 ± 9 years old, 76% men) are enrolled. The CS was identified in 95 patients and, in 85 (88.5%), the LV lead was successfully implanted. The final lead positioning was lateral in 41%, posterolateral in 35%, anterolateral in 18%, and great cardiac vein in 6% of patients. In 70%, the 85 successful implantations, both stylet-driven and guide-wire techniques were used, a stylet only was used in 22%, and a guide wire only in 8%. Mean overall duration of 85 successful procedures was 112 ± 40 minutes, total fluoroscopy time 28 ± 15 minutes, and the duration of LV lead placement was 35 ± 29 minutes. During a 3-month follow-up, the loss of LV capture occurred in three and phrenic nerve stimulation in six patients. The mean long-term pacing threshold is 0.8 V/0.5 ms and pacing impedance is 550 Ω. The OVID data suggest that these new leads are safe and effective. The choice of both OTW and SD techniques during lead implantation offers greater procedural flexibility.

Original languageEnglish
Pages (from-to)S31-S35
JournalPACE - Pacing and Clinical Electrophysiology
Issue numberSUPPL. 1
Publication statusPublished - Jan 1 2005


  • Cardiac resynchronization therapy
  • Endocardial left ventricular lead
  • Left ventricular lead
  • Pacing lead implantation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Ellery, S., Paul, V., Prenner, G., Tscheliessnigg, K., Merkely, B., Malinowski, K., Fröhlig, G., Hintringer, F., Bosse, O., Diotallevi, P., Ravazzi, A. P., Flathmann, H., Danilovic, D., & Unterberg-Buchwald, C. (2005). A new endocardial "over-the-wire" or stylet-driven left ventricular lead: First clinical experience. PACE - Pacing and Clinical Electrophysiology, 28(SUPPL. 1), S31-S35. https://doi.org/10.1111/j.1540-8159.2005.00084.x