A new derivatization reaction was developed for the characterization of organic acids by electrospray ionization mass spectrometry in the highly sensitive positive-ion mode, using N,N'-dicyclohexylcarbodiimide and N,N'-dimethylethylenediamine. Suitability of the reaction was demonstrated on different types of organic acids. When selected-ion monitoring was applied, the detection limit was at the low femtomol level.
|Number of pages||3|
|Journal||Rapid Communications in Mass Spectrometry|
|Publication status||Published - Jan 1 1997|
ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry