A new bipodal carboxy-bis(hydroxypyridinonate) ligand. Synthesis and complexation with copper(II), nickel(II) and zinc(II) in aqueous solution

M. Amélia Santos, Raquel Grazina, P. Buglyó, Sofia Gama, E. Farkas

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A new tetradentate ligand having two 3-hydroxy-4-pyridinonate moieties and one carboxylate group appended to a cyclohexane backbone is reported, together with the corresponding bidentate hydroxypyridinonate pendant arm. The synthesis and characterization of these ligands, as well as their complexation properties towards the first transition series of metal ions M(II) (M = Cu, Ni, Zn) in aqueous solution, are described and discussed herein. The tetradentate ligand forms quite stable complexes with this series of metal ions and in solution, it is proved to be a much more effective chelator than the corresponding bidentate derivative. The stability constants of the complexes formed with this set of bivalent ions follow the Irving-Williams order Ni <Cu > Zn. The carboxylic group has no interaction with the metal centre, thus remaining free for potential interaction with biological ligands (e.g. proteins).

Original languageEnglish
Pages (from-to)2609-2616
Number of pages8
JournalPolyhedron
Volume21
Issue number25-26
Publication statusPublished - Dec 1 2002

Fingerprint

Nickel
Complexation
Zinc
Copper
zinc
Ligands
nickel
aqueous solutions
copper
ligands
Metals
Ions
synthesis
Metal ions
metal ions
Cyclohexane
Chelating Agents
cyclohexane
carboxylates
interactions

Keywords

  • Bifunctional ligand
  • Chelating agents
  • Hydroxypyridinonate complexes
  • Hydroxypyridinones

ASJC Scopus subject areas

  • Biochemistry
  • Inorganic Chemistry
  • Physical and Theoretical Chemistry
  • Materials Chemistry

Cite this

A new bipodal carboxy-bis(hydroxypyridinonate) ligand. Synthesis and complexation with copper(II), nickel(II) and zinc(II) in aqueous solution. / Amélia Santos, M.; Grazina, Raquel; Buglyó, P.; Gama, Sofia; Farkas, E.

In: Polyhedron, Vol. 21, No. 25-26, 01.12.2002, p. 2609-2616.

Research output: Contribution to journalArticle

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