A model for histone nonhistone control of ontogenesis

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

The co-operation of histones and nonhistones in the known models can sufficiently explain the control of processes occurring within the differentiated cells. To give an explanation, on the same basis, for changes during ontogenesis and for manifestation of the development's program, a new model is needed which supposes the existence of a programming as well as a realizing system. At the start, the realizing system becomes repressed by histones. After this, the programming system gives orders for the production of nonhistones. These latter then activate the adequate (definite) operator of the realizing system and direct, simultaneously, a further programming gene for the production of a specific nonhistone needed for the following step of the program. Further on, the model could give an explanation for the manner in which the differentiated features of the cell are conserved during mitosis. One may suppose, in this case, that the new DNA strands become without delay wholly repressed. The phase-specific nonhistones, characterizing the cell's ontogenesis and produced by direction of the programming genes, will then displace the histones from the adequate DNA-sites.

Original languageEnglish
Title of host publicationRevue Roumaine de Morphologie, d'Embryologie et de Physiologie - Serie Morphologie et d'Embryologie
Pages19-26
Number of pages8
Volume23
Edition1
Publication statusPublished - 1977

Fingerprint

Histones
DNA
Mitosis
Genes
Direction compound

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Csaba, G. (1977). A model for histone nonhistone control of ontogenesis. In Revue Roumaine de Morphologie, d'Embryologie et de Physiologie - Serie Morphologie et d'Embryologie (1 ed., Vol. 23, pp. 19-26)

A model for histone nonhistone control of ontogenesis. / Csaba, G.

Revue Roumaine de Morphologie, d'Embryologie et de Physiologie - Serie Morphologie et d'Embryologie. Vol. 23 1. ed. 1977. p. 19-26.

Research output: Chapter in Book/Report/Conference proceedingChapter

Csaba, G 1977, A model for histone nonhistone control of ontogenesis. in Revue Roumaine de Morphologie, d'Embryologie et de Physiologie - Serie Morphologie et d'Embryologie. 1 edn, vol. 23, pp. 19-26.
Csaba G. A model for histone nonhistone control of ontogenesis. In Revue Roumaine de Morphologie, d'Embryologie et de Physiologie - Serie Morphologie et d'Embryologie. 1 ed. Vol. 23. 1977. p. 19-26
Csaba, G. / A model for histone nonhistone control of ontogenesis. Revue Roumaine de Morphologie, d'Embryologie et de Physiologie - Serie Morphologie et d'Embryologie. Vol. 23 1. ed. 1977. pp. 19-26
@inbook{6d62f026c12d43d4a89d3bfcb8d14149,
title = "A model for histone nonhistone control of ontogenesis",
abstract = "The co-operation of histones and nonhistones in the known models can sufficiently explain the control of processes occurring within the differentiated cells. To give an explanation, on the same basis, for changes during ontogenesis and for manifestation of the development's program, a new model is needed which supposes the existence of a programming as well as a realizing system. At the start, the realizing system becomes repressed by histones. After this, the programming system gives orders for the production of nonhistones. These latter then activate the adequate (definite) operator of the realizing system and direct, simultaneously, a further programming gene for the production of a specific nonhistone needed for the following step of the program. Further on, the model could give an explanation for the manner in which the differentiated features of the cell are conserved during mitosis. One may suppose, in this case, that the new DNA strands become without delay wholly repressed. The phase-specific nonhistones, characterizing the cell's ontogenesis and produced by direction of the programming genes, will then displace the histones from the adequate DNA-sites.",
author = "G. Csaba",
year = "1977",
language = "English",
volume = "23",
pages = "19--26",
booktitle = "Revue Roumaine de Morphologie, d'Embryologie et de Physiologie - Serie Morphologie et d'Embryologie",
edition = "1",

}

TY - CHAP

T1 - A model for histone nonhistone control of ontogenesis

AU - Csaba, G.

PY - 1977

Y1 - 1977

N2 - The co-operation of histones and nonhistones in the known models can sufficiently explain the control of processes occurring within the differentiated cells. To give an explanation, on the same basis, for changes during ontogenesis and for manifestation of the development's program, a new model is needed which supposes the existence of a programming as well as a realizing system. At the start, the realizing system becomes repressed by histones. After this, the programming system gives orders for the production of nonhistones. These latter then activate the adequate (definite) operator of the realizing system and direct, simultaneously, a further programming gene for the production of a specific nonhistone needed for the following step of the program. Further on, the model could give an explanation for the manner in which the differentiated features of the cell are conserved during mitosis. One may suppose, in this case, that the new DNA strands become without delay wholly repressed. The phase-specific nonhistones, characterizing the cell's ontogenesis and produced by direction of the programming genes, will then displace the histones from the adequate DNA-sites.

AB - The co-operation of histones and nonhistones in the known models can sufficiently explain the control of processes occurring within the differentiated cells. To give an explanation, on the same basis, for changes during ontogenesis and for manifestation of the development's program, a new model is needed which supposes the existence of a programming as well as a realizing system. At the start, the realizing system becomes repressed by histones. After this, the programming system gives orders for the production of nonhistones. These latter then activate the adequate (definite) operator of the realizing system and direct, simultaneously, a further programming gene for the production of a specific nonhistone needed for the following step of the program. Further on, the model could give an explanation for the manner in which the differentiated features of the cell are conserved during mitosis. One may suppose, in this case, that the new DNA strands become without delay wholly repressed. The phase-specific nonhistones, characterizing the cell's ontogenesis and produced by direction of the programming genes, will then displace the histones from the adequate DNA-sites.

UR - http://www.scopus.com/inward/record.url?scp=0017610740&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017610740&partnerID=8YFLogxK

M3 - Chapter

VL - 23

SP - 19

EP - 26

BT - Revue Roumaine de Morphologie, d'Embryologie et de Physiologie - Serie Morphologie et d'Embryologie

ER -