A Hungarian study on Werdnig-Hoffmann disease

E. Czeizel, János Hamula

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

The prevalence of Werdnig-Hoffmann disease was found to be 0.66 per 10 000 livebirths in Hungary from 1973 to 1980. However, the true prevalence is estimated to be 1 per 10 000 livebirths, which exceeds the level of a previously published English study. There was no higher fetal death rate in previous and subsequent pregnancies of index patients' mothers. The occurrence in sibs was 32%, probably because of greater ascertainment in families with more than one affected child.

Original languageEnglish
Pages (from-to)761-763
Number of pages3
JournalJournal of Medical Genetics
Volume26
Issue number12
DOIs
Publication statusPublished - 1989

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Spinal Muscular Atrophies of Childhood
death rate
Hungary
pregnancy
Disease
Fetal Death
Mothers
Pregnancy
Mortality

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health(social science)
  • Genetics
  • Genetics(clinical)

Cite this

A Hungarian study on Werdnig-Hoffmann disease. / Czeizel, E.; Hamula, János.

In: Journal of Medical Genetics, Vol. 26, No. 12, 1989, p. 761-763.

Research output: Contribution to journalArticle

Czeizel, E. ; Hamula, János. / A Hungarian study on Werdnig-Hoffmann disease. In: Journal of Medical Genetics. 1989 ; Vol. 26, No. 12. pp. 761-763.
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