A highly accurate determination of absorbed power during magnetic hyperthermia

I. Gresits, Gy Thuróczy, O. Sági, I. Homolya, G. Bagaméry, D. Gajári, M. Babos, P. Major, B. G. Márkus, F. Simon

Research output: Contribution to journalArticle

Abstract

Absorbed power of nanoparticles during magnetic hyperthermia can be well determined from changes in the quality factor (Q factor) of a resonator in which the radiofrequency absorbent is placed. We present an order of magnitude improvement in the Q factor measurement accuracy over conventional methods by studying the switch-on and off transient signals of the resonators. A nuclear magnetic resonance console is ideally suited to acquire the transient signals and it also allows to employ the so-called pulse phase-cycling to remove transient artifacts. The improved determination of the absorbed power is demonstrated on various resonators in the 1-30 MHz range, including standard solenoids and also a birdcage resonator. This leads to the possibility to detect minute amounts of ferrite nanoparticles which are embedded in the body and also the amount of the absorbed power. We demonstrate this capability on a phantom study, where the exact location of an embedded ferrite is clearly detected.

Original languageEnglish
Article number375401
JournalJournal of Physics D: Applied Physics
Volume52
Issue number37
DOIs
Publication statusPublished - Jul 12 2019

Fingerprint

hyperthermia
Resonators
resonators
Ferrite
Q factors
ferrites
consoles
Nanoparticles
nanoparticles
Solenoids
absorbents
solenoids
artifacts
switches
Switches
Nuclear magnetic resonance
nuclear magnetic resonance
cycles
pulses

Keywords

  • Fourier transform
  • hyperthermia
  • pulses
  • quality factor
  • resonance
  • time domain techniques

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Acoustics and Ultrasonics
  • Surfaces, Coatings and Films

Cite this

A highly accurate determination of absorbed power during magnetic hyperthermia. / Gresits, I.; Thuróczy, Gy; Sági, O.; Homolya, I.; Bagaméry, G.; Gajári, D.; Babos, M.; Major, P.; Márkus, B. G.; Simon, F.

In: Journal of Physics D: Applied Physics, Vol. 52, No. 37, 375401, 12.07.2019.

Research output: Contribution to journalArticle

Gresits, I, Thuróczy, G, Sági, O, Homolya, I, Bagaméry, G, Gajári, D, Babos, M, Major, P, Márkus, BG & Simon, F 2019, 'A highly accurate determination of absorbed power during magnetic hyperthermia', Journal of Physics D: Applied Physics, vol. 52, no. 37, 375401. https://doi.org/10.1088/1361-6463/ab27f4
Gresits I, Thuróczy G, Sági O, Homolya I, Bagaméry G, Gajári D et al. A highly accurate determination of absorbed power during magnetic hyperthermia. Journal of Physics D: Applied Physics. 2019 Jul 12;52(37). 375401. https://doi.org/10.1088/1361-6463/ab27f4
Gresits, I. ; Thuróczy, Gy ; Sági, O. ; Homolya, I. ; Bagaméry, G. ; Gajári, D. ; Babos, M. ; Major, P. ; Márkus, B. G. ; Simon, F. / A highly accurate determination of absorbed power during magnetic hyperthermia. In: Journal of Physics D: Applied Physics. 2019 ; Vol. 52, No. 37.
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