A heteroploid permanent cell line originating from embryonic calf thyroid supporting the replication of all known bovine adenovirus serotypes

Maria Benkö, A. Bartha, Karin Möstl, F. Bürki

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An embryonic calf thyroid cell culture was established as a permanent heteroploid cell line, which is now in its 150th subculture. It allowed replication of all nine bovine adenovirus serotypes at its 15th as well as its 60-150th passages. All viruses induced typical cytopathic effects. Yields obtained on the permanent calf thyroid line were, on average, 0.8 log10 lower than those obtained on primary calf testicle cells.

Original languageEnglish
Pages (from-to)317-324
Number of pages8
JournalVeterinary Microbiology
Issue number4
Publication statusPublished - Apr 1 1989


ASJC Scopus subject areas

  • Microbiology
  • veterinary(all)

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