A critical overview of the kabachnik-fields reactions utilizing trialkyl phosphites in water as the reaction medium

A study of the benzaldehyde- benzylamine triethyl phosphite/diethyl phosphite models

G. Keglevich, Erika Bálint, Réka Kangyal, Mária Bálint, Mátyás Milen

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

α-Aminophosphonates may be synthesized by the three-component condensation of oxo-compounds, amines, and dialkyl phosphites or trialkyl phosphites. In the latter case, mostly water is the reaction medium and a catalyst is also needed. This approach has been studied critically by us, exploring the background of this version of the Kabachnik-Fields condensation. The possibilities for the Kabachnik-Fields condensation of benzaldehyde, benzylamine, and triethyl phosphite or diethyl phosphite including the accomplishment in water were studied in detail.

Original languageEnglish
Pages (from-to)282-289
Number of pages8
JournalHeteroatom Chemistry
Volume25
Issue number4
DOIs
Publication statusPublished - 2014

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Phosphites
Condensation
Water
Amines
Catalysts
benzylamine
benzaldehyde
triethyl phosphite

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

A critical overview of the kabachnik-fields reactions utilizing trialkyl phosphites in water as the reaction medium : A study of the benzaldehyde- benzylamine triethyl phosphite/diethyl phosphite models. / Keglevich, G.; Bálint, Erika; Kangyal, Réka; Bálint, Mária; Milen, Mátyás.

In: Heteroatom Chemistry, Vol. 25, No. 4, 2014, p. 282-289.

Research output: Contribution to journalArticle

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