A convenient synthesis of pyrrolo[3,4-c]quinolines

Miklós Nyerges, A. Virányi, L. Tőke

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A new route to the pyrrolo[3-,4-c]quinoline ring system has been developed. The synthesis proceeds stereoselectively in three steps, using 1,3-dipolar cycloaddition of azomethine ylides as a key step. First, a series of 4-aryl-pyrrolidine-3-carboxylic acid has been prepared from the appropriate cinnamic esters and a non-stabilised azomethine ylide. The reduction of nitro group on the aromatic ring was followed by the acid catalyzed intramolecular lactame formation.

Original languageEnglish
Pages (from-to)239-242
Number of pages4
JournalHeterocyclic Communications
Volume9
Issue number3
Publication statusPublished - 2003

Fingerprint

Quinolines
Cycloaddition
Esters
Acids
azomethine
pyrrolidine-3-carboxylic acid
quinoline

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

A convenient synthesis of pyrrolo[3,4-c]quinolines. / Nyerges, Miklós; Virányi, A.; Tőke, L.

In: Heterocyclic Communications, Vol. 9, No. 3, 2003, p. 239-242.

Research output: Contribution to journalArticle

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