The two diastereomers of ethyl 3-methyl-1,2,3,4-tetrahydroisoquinoline-1-acetate (4 and 5) were synthesized from l-(3′,4′-dimethoxyphenyl)isopropylamine (1) by direct and reverse substituent introductions. The cause of the diastereo-stereoselectivity is rationalized.
|Number of pages||2|
|Publication status||Published - Dec 1 1996|
ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry