A comparison of European, Polish, Slovenian and British EQ-5D-3L value sets using a Hungarian sample of 18 chronic diseases

Zsombor Zrubka, Zsuzsanna Beretzky, Zoltán Hermann, Valentin Brodszky, L. Gulácsi, Fanni Rencz, Petra Baji, Dominik Golicki, Valentina Prevolnik-Rupel, Márta Péntek

Research output: Contribution to journalArticle

Abstract

Background: In the Central and Eastern European region, the British EQ-5D-3L value set is used commonly in quality of life (QoL) studies. Only Poland and Slovenia have country-specific weights. Our study aimed to investigate the impact of value set choice on the evaluation of 18 chronic conditions in Hungary. Methods: Patients’ EQ-5D-3L index scores were calculated using the VAS-based Slovenian and European and the time-trade-off-based Polish and British value sets. We performed pairwise comparisons of mean index values by dimensions, diagnoses and age groups. We evaluated disease burden by comparing index values matched by age and gender in each condition with those of the general population of the CEE region in all four value sets. Results: Altogether, 2421 patients (55% female) were included in our sample with the average age of 55.87 years (SD = 17.75). The average Slovenian, European, Polish and British EQ-5D-3L scores were 0.598 (SD = 0.279), 0.661 (SD = 0.257), 0.770 (SD = 0.261) and 0.644 (SD = 0.279), respectively. We found highly significant differences in most diagnoses, with the greatest difference between the Polish and Slovenian index values in Parkinson’s disease (0.265). Systematic pairwise comparison across all conditions and value sets revealed greatest differences between the time-trade-off (TTO) and VAS-based value sets as well as varying sensitivity of the disease burden evaluations of chronic disease conditions to the choice of value sets. Conclusions: Our results suggest that the choice of value set largely influences the health state utility results in chronic diseases, and might have a significant impact on health policy decisions.

Original languageEnglish
Pages (from-to)119-132
Number of pages14
JournalEuropean Journal of Health Economics
Volume20
DOIs
Publication statusPublished - Jun 1 2019

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Chronic Disease
Slovenia
Hungary
Poland
Health Policy
Parkinson Disease
Age Groups
Quality of Life
Weights and Measures
Health
Population
Chronic disease

Keywords

  • Chronic disease
  • Disease burden
  • EQ-5D-3L
  • Hungary
  • Poland
  • Quality of life
  • Slovenia
  • Value set

ASJC Scopus subject areas

  • Economics, Econometrics and Finance (miscellaneous)
  • Health Policy

Cite this

A comparison of European, Polish, Slovenian and British EQ-5D-3L value sets using a Hungarian sample of 18 chronic diseases. / Zrubka, Zsombor; Beretzky, Zsuzsanna; Hermann, Zoltán; Brodszky, Valentin; Gulácsi, L.; Rencz, Fanni; Baji, Petra; Golicki, Dominik; Prevolnik-Rupel, Valentina; Péntek, Márta.

In: European Journal of Health Economics, Vol. 20, 01.06.2019, p. 119-132.

Research output: Contribution to journalArticle

Zrubka, Z, Beretzky, Z, Hermann, Z, Brodszky, V, Gulácsi, L, Rencz, F, Baji, P, Golicki, D, Prevolnik-Rupel, V & Péntek, M 2019, 'A comparison of European, Polish, Slovenian and British EQ-5D-3L value sets using a Hungarian sample of 18 chronic diseases', European Journal of Health Economics, vol. 20, pp. 119-132. https://doi.org/10.1007/s10198-019-01069-8
Zrubka, Zsombor ; Beretzky, Zsuzsanna ; Hermann, Zoltán ; Brodszky, Valentin ; Gulácsi, L. ; Rencz, Fanni ; Baji, Petra ; Golicki, Dominik ; Prevolnik-Rupel, Valentina ; Péntek, Márta. / A comparison of European, Polish, Slovenian and British EQ-5D-3L value sets using a Hungarian sample of 18 chronic diseases. In: European Journal of Health Economics. 2019 ; Vol. 20. pp. 119-132.
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AU - Beretzky, Zsuzsanna

AU - Hermann, Zoltán

AU - Brodszky, Valentin

AU - Gulácsi, L.

AU - Rencz, Fanni

AU - Baji, Petra

AU - Golicki, Dominik

AU - Prevolnik-Rupel, Valentina

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